Bacterial Biophysics and bottom up biology
Nanofabricated structures and bacterial growth therein
We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks. With this approach, we assess the fundamental role of spatial confinement at the molecular, cellular and population level in biology. We use a bottom-up approach to recapture the main events occurring in cell division in vitro, working towards the aim to realize synthetic cell division.
Our current research focuses on: