Exploring life at the nanoscale
@nanoscale_rsc @mitashabharadw NB Today’s paper was the result of a brainstorm idea, 8 years back at a group retreat, by @felixhol (then in our #CDlab, now PI at Pasteur). A simple but inspiring idea
which started a project
that turned out -of course- to be less easy than foreseen
but with a nice result today https://t.co/xZ3Zumy6uq 
Latest #CDlab paper online in @nanoscale_rsc:
‘CRISPR-dCas9 based DNA detection scheme for diagnostics in resource-limited settings’ https://t.co/ucMVImm3Oy Here, Michel Bengtson, @mitashabharadw, Oskar Franch, and others show a new cheap Crispr-based test for neglected diseases https://t.co/CMzRO9vfVu 
Hier wat gave ideeën voor concrete kleinschalige acties om te werken aan een meer sustainable toekomst – van @sciforfuture_NL, een groep promovendi van @TUDelft met o.a. promovendus Nils van ons #CDlab. https://t.co/qYfntFQynh
Nice ‘research highlight’ perspective in @naturemethods on the work towards single-molecule protein sequencing from our #CDlab and @MagliaGiovanni https://t.co/7hzxjRGD7Q https://t.co/N33tE54Xz3 
Now out in @NAR_Open:
Our #CDlab paper that resolves the ~30 nm single steps that SMC proteins make during DNA loop extrusion: https://t.co/32qRnljhqw Title says it all:
Condensin extrudes DNA loops in steps up to hundreds of base pairs that are generated by ATP binding events. https://t.co/Ag2VbbgwlH 
ànd yet another #CDlab paper at @biorxivpreprint: https://t.co/Heoja9h5tV Here, @AlessioFragasso combines our biomimetics with MD simulations by @deVriesHW from Patrick Onck’s lab to study how transport receptors are an essential part of the Nuclear Pore Complex
#KapCentricModel https://t.co/sBTvGwowYb 
Latest #CDlab paper at @biorxivpreprint: A synthetic membrane shaper for controlled liposome deformation https://t.co/a86wuMZhJa Here Nicola De Franceschi shows that DNA on liposomes can generate high yields of stomatocyte or dumbbell shapes. Great collaboration with @CG_Martini https://t.co/D2Rx7VQEcm 
Its so inspiring to see former graduate students of our #CDlab branch out and build their own careers. Listen for example to this short statement of @calinplesa, now assistant professor at Oregon https://t.co/s8gO4bFeS0
Upcoming! The 1st BaSyC seminar in the @buildacell seminar series. Nicola De Franceschi “Towards a synthetic divisome: Dynamin A and the Synthetic Membrane Shaper” Monday 6 December at 11AM Central Time (= 6 PM CET) https://t.co/1PjOskvx3z #CDlab #syntheticcells @SynCellEU
Our latest preprint: https://t.co/tn2jykKI7m Here, @LWuerthner & Fridtjof Brauns from @PhysOfLifeLMU develop a model for multiscale patterns in spatially heterogeneous geometries. And Greg Pawlik from our #CDlab confirmed this with experiments on Min protein patterns in a wedge https://t.co/nGtwzjJPj3 
Nice to see the OLA giant unilamellar vesicle production method, that we developed in our #CDlab when @SiddhuLab was a postdoc here, getting commercialised https://t.co/OiKmYNJ1BF
@cees_dekker @ScienceMagazine @aksimentievLab This is awesome! Congrats @cees_dekker #CDlab
Today we publish a paper in @ScienceMagazine that expands nanopore readings to the proteome:
a nanopore-based scanner to read off PROTEINS at the single-molecule level! 🤩 Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, with MD simulations of @aksimentievLab 1/x https://t.co/NU7oKQuNgN 
New #CDlab @biorxivpreprint: https://t.co/70Os03I44l Here, 1st author @TismaMilos discovered a new mechanism of how the bacterial chromosome-partitioning protein ParB can recruit new ParB on DNA, independently of parS. Great collaboration with @Gruber_Lausanne & @Dmichiel1 https://t.co/a4PC1JoCsx 
We significantly updated our #CDlab preprint paper about the step size of SMC proteins in DNA loop extrusion – see here for the new version on @biorxivpreprint: https://t.co/oLTkq9sb5y https://t.co/Y2EZDJzr29 
What is that #CDlab about? Our Bionanoscience department made a brief item introducing our group – including interviews with PhD students Sabrina Meindlhumer, @RomanBarth2, and @AlessioFragasso : https://t.co/AdZTA8GGhv
Cool paper out in @NatureComms by #BerndRieger/@SjoerdStallinga labs, to which our #CDlab also contributed: https://t.co/F3whWcUri4 Phase plate 2D imaging allows to determine both 3D position ànd orientation of a single fluorophore. Used this to optically image DNA supercoils! https://t.co/hzwaF15f7Y 
Latest paper #CDlab online:
‘FIB-milled plasmonic nanoapertures allow for long trapping times of individual proteins’ https://t.co/U8s8MopCdp Here, 1st author @Wayne_YangWW reports a FIB technique to make arrays of plasmonic nanopores that can hold single proteins for long times https://t.co/YHjx64TsdX 
New preprint of our #CDlab: “The archaeal division protein CdvB1 assembles into polymers that are depolymerized by CdvC” https://t.co/vP7lZnSZVX Here, we investigated some of the unique cell division machinery of archaea in vitro. Congrats to 1st author @abejota94 and coworkers https://t.co/2swmAw1Lis 
