Exploring life at the nanoscale
Our latest #CDlab paper online: https://t.co/342WOKyiFM PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA, in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores https://t.co/m6LKypiDkT 
Congrats to @tudelft colleague Farbod Alijani for getting an @ERC proof-of-concept grant to develop graphene sensors for sensing single bacteria (to which our #CDlab may also will contribute a bit) https://t.co/5uvOaD5l9y https://t.co/lf624sf9Zx
Genome-in-a-box or GenBox? The name comes from the ‘particle-in-a-box’ models that provided basic insights in quantum mechanics. Similarly, using a bottom up biology approach we hope that GenBox may help to unravel key properties of chromosome organization.
#CDlab #MoreToFollow https://t.co/cr6ZH0AHB2 
Thanks to @martinholub_ @eugene_kim__ Jaco van der Torre and Aleksandre Japaridze for their discussions and feedback on the manuscript. As always, one never does science alone! #CDlab https://t.co/cYlxiEM7Q8
Paper online in @acsnano!
In this perspective/review, @cees_dekker and I argue for a new in vitro approach to build and study chromosomes.
Take megabasepair DNA, add individual chromosome building blocks, and build a chromosome from the bottom up. https://t.co/6ICzIW26dO #CDlab https://t.co/jgMYkpWMx4 
Our latest #CDlab paper online in @acsnano!
In this perspective/review, @AnthonyBirnie and I argue for a new in vitro approach to build and study chromosomes:
Take megabasepair DNA, study individual building blocks, and then build a chromosome bottom up. https://t.co/5DrbXqfj7f https://t.co/K2c04stYcD 
Here’s a very nice ‘Goodbye’ video by Korean postdoc @JeKyungRyu1 where he captured lots of informal nonscience aspects of our wonderfully social science group, the #CDlab: https://t.co/O0GSx1BhnO
On January 13, we organize an afternoon symposium on ‘New Technology in the Diagnostics of Poverty-related Parasitic Diseases’ All welcome to join in!
Free admission, but register here: https://t.co/GnT9TDghlV #TUDelftGlobalInitiative #CDlab https://t.co/9ixQYDt18u 
Latest #CDlab preprint on @biorxivpreprint: https://t.co/BlLyfZc7u0 We resolved individual steps of a condensin SMC while it extrudes loops of DNA – translocating DNA up to 600 bp/step with a step size of 20-45 nm. We find that ATP _binding_ generates the steps in loop extrusion https://t.co/WVuPGa6ho0 
Dear #nanopore friends, don’t miss @cees_dekker ‘s talk this afternoon (2:40pm CEST). For the first time, he will present our #NEOtrap for long-term protein sensing using solid-state nanopores, plus many other exciting projects at #CDlab. See you online!😀 https://t.co/VIQXIQMp79
Latest #CDlab paper online in @GHSPJournal: https://t.co/faaKkVEctx Matching development of point-of-care diagnostic tests to the local context: A case study of visceral leishmaniasis in Kenya and Uganda Great work by Michel Bengtson @mitashabharadw together with group @jcdiehl https://t.co/5lAD6G8Rsr 
Our latest #CDlab paper is on @arxiv: https://t.co/VzP66nIGMe PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores https://t.co/tWQd6MSaHF 
Our AFM paper is published in NSMB today in a collaboration with #CDlab and the Haering lab at EMBL. We suggested a scrunching model for SMC-protein-mediated DNA loop extrusion based on our observations. A HS-AFM movie of a condensin with ATP : https://t.co/u8Lu3BnQEE
Out now in @NatureSMB, our paper reporting liquid-AFM images of open and collapsed states of yeast condensin and the dynamic toggling between such states: https://t.co/0t2HaDYf5o Great job by postdoc @JeKyungRyu1 from our #CDlab in a collaboration with the Haering lab at EMBL. https://t.co/bKojIw7D4u 
Refugees in the Netherlands with a MSc or PhD and relevant expertise in bio/nano/physics are welcome to contact me for a possible position in our #CDlab https://t.co/UxV0WyNBwc https://t.co/X8SP55XW2e
Heerlijke middag en avond gehad met alle leden van ons #CDlab: museum Voorlinden, kleiduiven schieten, beach volleybal en lekker een biertje en BBQ met alle partners en gezinnen bij een strandtent. Genieten! https://t.co/72FA0xWCm5 
Openings for 4 PhD students and 4 Postdoctoral researchers for research on intrinsically disordered proteins in the Netherlands: https://t.co/pPGZh80hJ8 Join the great biologists / computational group at Groningen,
or our biophysics #CDlab at Delft: https://t.co/KYPrWGziVE https://t.co/nUXyIaMcNN 
Postdoc and co-1st author @KevinDWhitley sketches the background story of our latest paper on the role of FtsZ treadmlling (https://t.co/AOnNDGudYl ) by @seamus_holden lab and our #CDlab: https://t.co/AlVQmwv6bx Artwork by @LizahvdA https://t.co/3e83eQ5F7j 
So why is FtsZ actually treadmilling in bacterial cell division? @KevinDWhitley, a joint postdoc with @seamus_holden & our #CDlab, sorted it out: This is essential for Z-ring condensation and septal constriction initiation. Great work, now at @BioRxiv: https://t.co/AOnNDGudYl https://t.co/tW1SD4tTCH
Nice:
@AnneMirabella, senior editor of @NatureComms, selected our paper on imaging the circular chromosome of a bacterium (https://t.co/8fE0vXvn8o ) as a highlight of the past year: https://t.co/mrhw2kDjka Work led by postdocs @fabaiwu and Sandro Japaridze at our #CDlab https://t.co/YsovBMem2x 
