Exploring life at the nanoscale
Latest #CDlab preprint on @biorxivpreprint: https://t.co/BlLyfZc7u0 We resolved individual steps of a condensin SMC while it extrudes loops of DNA – translocating DNA up to 600 bp/step with a step size of 20-45 nm. We find that ATP _binding_ generates the steps in loop extrusion https://t.co/WVuPGa6ho0 
Dear #nanopore friends, don’t miss @cees_dekker ‘s talk this afternoon (2:40pm CEST). For the first time, he will present our #NEOtrap for long-term protein sensing using solid-state nanopores, plus many other exciting projects at #CDlab. See you online!😀 https://t.co/VIQXIQMp79
Latest #CDlab paper online in @GHSPJournal: https://t.co/faaKkVEctx Matching development of point-of-care diagnostic tests to the local context: A case study of visceral leishmaniasis in Kenya and Uganda Great work by Michel Bengtson @mitashabharadw together with group @jcdiehl https://t.co/5lAD6G8Rsr 
Our latest #CDlab paper is on @arxiv: https://t.co/VzP66nIGMe PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores https://t.co/tWQd6MSaHF 
Our AFM paper is published in NSMB today in a collaboration with #CDlab and the Haering lab at EMBL. We suggested a scrunching model for SMC-protein-mediated DNA loop extrusion based on our observations. A HS-AFM movie of a condensin with ATP : https://t.co/u8Lu3BnQEE
Out now in @NatureSMB, our paper reporting liquid-AFM images of open and collapsed states of yeast condensin and the dynamic toggling between such states: https://t.co/0t2HaDYf5o Great job by postdoc @JeKyungRyu1 from our #CDlab in a collaboration with the Haering lab at EMBL. https://t.co/bKojIw7D4u 
Refugees in the Netherlands with a MSc or PhD and relevant expertise in bio/nano/physics are welcome to contact me for a possible position in our #CDlab https://t.co/UxV0WyNBwc https://t.co/X8SP55XW2e
Heerlijke middag en avond gehad met alle leden van ons #CDlab: museum Voorlinden, kleiduiven schieten, beach volleybal en lekker een biertje en BBQ met alle partners en gezinnen bij een strandtent. Genieten! https://t.co/72FA0xWCm5 
Openings for 4 PhD students and 4 Postdoctoral researchers for research on intrinsically disordered proteins in the Netherlands: https://t.co/pPGZh80hJ8 Join the great biologists / computational group at Groningen,
or our biophysics #CDlab at Delft: https://t.co/KYPrWGziVE https://t.co/nUXyIaMcNN 
Postdoc and co-1st author @KevinDWhitley sketches the background story of our latest paper on the role of FtsZ treadmlling (https://t.co/AOnNDGudYl ) by @seamus_holden lab and our #CDlab: https://t.co/AlVQmwv6bx Artwork by @LizahvdA https://t.co/3e83eQ5F7j 
So why is FtsZ actually treadmilling in bacterial cell division? @KevinDWhitley, a joint postdoc with @seamus_holden & our #CDlab, sorted it out: This is essential for Z-ring condensation and septal constriction initiation. Great work, now at @BioRxiv: https://t.co/AOnNDGudYl https://t.co/tW1SD4tTCH
Nice:
@AnneMirabella, senior editor of @NatureComms, selected our paper on imaging the circular chromosome of a bacterium (https://t.co/8fE0vXvn8o ) as a highlight of the past year: https://t.co/mrhw2kDjka Work led by postdocs @fabaiwu and Sandro Japaridze at our #CDlab https://t.co/YsovBMem2x 
Latest paper online:
“A Mechanically Tunable Quantum Dot in a Graphene Break Junction” https://t.co/qhqf9ShcXo Great work by postdoc Sabina Caneva (now PI at Delft) where our #CDlab contributed in a collaboration with het labs of Herre van der Zant and Jaime Ferrer https://t.co/74SkAk6HGc 
Great!
Our latest #CDlab paper out today in @NatureComms: https://t.co/Qbi7imBqvV Postdoc Alexandre Japaridze visualized DNA replication and segregation in shape-manipulated bacteria, providing direct support for the train-track model with independent replication bubbles. https://t.co/7clsDZyjUk 
Science is an international enterprise without borders. Here’s our #CDlab with and without foreign immigrants. https://t.co/9VStjwXZRa 
Exciting finding:
The cohesin SMC complex is not only a DNA-loop extruder but can also induce phase separation! Now at @biorxivpreprint: https://t.co/7uWBzkJeE7 Check out this major surprise! Great work of postdoc @JeKyungRyu1 at #CDlab together with #Uhlmann & @Dmichiel1 labs. https://t.co/Ieb7nincD5 
Our latest #CDlab paper online now in @acsnano! pH-Controlled Coacervate-Membrane Interactions within Liposomes https://t.co/7Y60w5HVtk We show a new way to control phase condensation and study their interaction to membranes. Great work by master student #MartLast & @SiddhuLab. https://t.co/XqZaezbI65 
Hoogleraar @cees_dekker van de @tudelft ontving onlangs zijn derde @ERC_Research grant. Met de subsidie is hij van plan bottom-up een #chromosoom te bouwen. https://t.co/RbJUxVRTEt #genomeinabox #biophysics #CDlab https://t.co/sRSFkmIwv7 
Repeated news (since I forgot to include #CDlab hashtag to get it on the lab website) I got awarded a 3rd ERC Advanced Grant!
This allows us to work on SMC proteins & chromosome biophysics in the next 5 years. With a ‘genome in a box’ approach we’ll build a chromosome bottom up! https://t.co/Fv3BwLoiRi 
Hey, a non-corona tweet! Here’s our latest paper ‘Interplay between Confinement and Drag Forces Determine the Fate of Amyloid Fibrils’ in @PhysRevLett, nice work of Raffaele Mezzenga lab where our #CDlab contributed microstructuring by Sandro Japaridze: https://t.co/fYVYg8bGpg https://t.co/xrK1ySzQy4 
