Latest #CDlab news
View #CDLab on Twitter Our latest paper online: https://t.co/9XFVPrkiCd Here, @LWuerthner & Fridtjof Brauns of @PhysOfLifeLMU develop a model for multiscale patterns in spatially heterogeneous geometries. Greg Pawlik from our #CDlab confirmed this with experiments on Min protein patterns in a wedge. https://t.co/j9FRydQkT1



Our latest paper online: https://t.co/9XFVPrkiCd Here, @LWuerthner & Fridtjof Brauns of @PhysOfLifeLMU develop a model for multiscale patterns in spatially heterogeneous geometries. Greg Pawlik from our #CDlab confirmed this with experiments on Min protein patterns in a wedge. https://t.co/j9FRydQkT1



Now online in @NaturePhysics:
our #CDlab paper on a nanoscale rotary machine that we built, a simple DNA bundle that self-organizes into a rotor that autonomously rotates at 10 Hz, as driven by a flow through a nanopore. ๐คฉ See https://t.co/MX57UqKqbU https://t.co/rVR9hOplvm



Latest #CDlab preprint at @bioRxiv: https://t.co/CEx0Oxncsi Here, we evaluate recent pseudotopological models for SMC-driven loop extrusion that attempted to explain the passage of large roadblocks into DNA loops that are extruded. Our data are found to not support these models https://t.co/jNJM5thwq3



Latest #CDlab paper online now: https://t.co/pNqQj5BUt7 Here, Sabrina Meindlhumer,
@jacobkers and me developed a methodic toolbox to quantitatively analyze surface wave patterns of Min proteins – the fascinating Turing patterns that some bacteria use in cell division. https://t.co/MizIorsxDM



WORK Obviously this also means that our #CDlab has now multiple openings for outstanding postdocs and PhD students! Feel free to contact: https://t.co/KYPrWGziVE https://t.co/iHx9DsVlAG
How about a reaction where a H and an Aryl moiety would exchange places? Sounds interesting? Then take a look @angew_chem, just accepted! #openaccess @FWFOpenAccess @AJF_Chem @lumieredelamont @Boehringer #CDLab https://t.co/54FulFhJsU https://t.co/3p4Nctn0V5



Great teamwork done by @cees_dekker and #AlejandroGonzalez, @BisLightyear, #JacovanderTorre! It was such a fun time to work in #CDlab as a postdoc (3/3).
My postdoctoral work in #CDlab is finally out @NatureSMB! In this work, we used single-molecule imaging to study how condensin navigates the under- and overwound DNA states (DNA supercoiling) abundant throughout the genome (1/3). ๐๐๐ https://t.co/4wq0LbGGmD
Latest #CDlab online in @NatureSMB: https://t.co/iHQ33T7coT SMC proteins can extrude loops of DNA.
DNA is often supercoiled.
But how do these effects interplay? Using single-molecule visualization, 1st author @eugene_kim__ resolved how these 2 effects work together. 1/3 https://t.co/WUkdV89edc



Latest #CDlab preprint on @biorxivpreprint: https://t.co/GpikqxZ8HZ This study led by 1ste author @AleksandreJapa, examines how the bacterial SMC complex MukBEF shapes chromosome architecture and segregation in E. coli cells, which we widened for these experiments. Have a read https://t.co/LklUnWieCX



Latest #CDlab preprint on @biorxivpreprint: https://t.co/GpikqxZ8HZ This study led by 1ste author @AleksandreJapa, examines how the bacterial SMC complex MukBEF shapes chromosome architecture and segregation in E. coli cells, which we widened for these experiments. Have a read https://t.co/LklUnWieCX



Latest #CDlab paper online in @ScienceAdvances: https://t.co/trxKQzG92k Here, @TismaMilos discovered a new mechanism of how the bacterial protein ParB can recruit new ParB on DNA, independently of parS. This was a great collaboration with @Gruber_Lausanne
& @Dmichiel1 1/3 https://t.co/KHDHwjLMXU



resonates well with our own #CDlab practices to attract postdocs and PhD students https://t.co/bHKR67LAzf
New #CDlab paper on @biorxivpreprint https://t.co/hiJ0USzXyP Here @martinholub_ @AnthonyBirnie et al develop protocols to take a genome from a bacterium, strip it from 97-100% of its binding proteins, and use it for biophysics experiments on megabasepair long DNA! #GenomeInABox https://t.co/AQVvfpRu7Z



Our latest #CDlab paper online: https://t.co/wMcf2o9SZo Here, @AlessioFragasso combined experiments on biomimetic pores with MD simulations by
@deVriesHW from Patrick Onck’s lab to study how transport receptors are an essential part of the Nuclear Pore Complex
#KapCentricModel https://t.co/e8mwiu9dd9



Our #CDlab ex-postdoc @mitashabharadw is nominated as โrising starโ https://t.co/ufSaIkxVsy
NB All this was teamwork (see above), but most credits go to 1st author @xinshi_d, who led this challenge as postdoc in our #CDlab Xin is on the job market now and will continue this work as tenure track assistant professor. I greatly recommend him, so get him while you can!
19/ https://t.co/pxyULsEt3b



Today, we put 2 new #CDlab papers on the @arxiv preprint server โ which both report, in different ways, on demonstrating nanoscale rotary motors that are driven by a flow through a nanopore. https://t.co/hs8tyxGXAd https://t.co/4UCIC4fqyt 1 / https://t.co/yoqBgia3H4



So cool to meet these guys at the conference, from left to right: Derek Stein, (me,) @the_adam_hall, @KeyserLab Incredibly proud that these guys were postdocs in our #CDlab 15-20 years ago, and now professors at respectively Brown Univ, Virginia Tech/Wake Forest, Univ Cambridge! https://t.co/062ryMuoxi



Our research lines
Our research ranges from the biophysics of DNA to synthetic cells and beyond.
More on our research linesOur team
View list of team membersOur biophysics lab hosts a very international group of researchers.
