Exploring life at the nanoscale

First lab paper out today 🎉 on biorxiv: https://t.co/6Q4fQoU3tu: congrats to my student Lori and Lennard & Fede from @gijsjekoenderi1’s lab who led the effort, and to the entire team including the @DanelonLab and #CDlab s. Here’s to many more vesicles for #synbio for everyone!

And… another @biorxivpreprint: Optimized cDICE for efficient reconstitution of biological systems in giant unilamellar vesicles https://t.co/TeG6q7MQGM Great multilab collaboration led by labs of @KGanzinger & @gijsjekoenderi1, with contributions of #DanelonLab and our #CDlab. https://t.co/0IRVxpjVMw

Latest preprint online: Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules https://t.co/nvH8apyqN4 Great work by @AlessioFragasso, NicolaDeFrancesch & ElivdSluis from our #CDlab, together with PierreStoermer & @hendrik_dietz https://t.co/jkjB4U97Dt

Latest #CDlab paper in @scienceadvances: SMC complexes are not only DNA-loop extruders but can also induce a new type of phase separation! https://t.co/raxbFl0sJ3 Check out this major surprise! Great work led by postdoc @JeKyungRyu1 with #Uhlmann & @Dmichiel1 #Marenduzzo labs https://t.co/2mmyw9DNud

#openScience = Yes, you’ll get all #NEOtrap raw data. I mean, why not?? After submitting @HugelLab’s 1st #preprint, this seems to make me the 1st to open up #CDlab raw data, correct @cees_dekker? And will be continued @WUR. (Not new for me btw: https://t.co/6ewBSJ7g9F ) https://t.co/AEdfY90ZSf

Very proud of @anders_barth who today heard that he will get a prestigious Marie Curie grant! I am confident that with his advanced optical expertise, he will further boost our #CDlab work on biomimetic nuclear pore complexes to yield some great science. Congrats!! https://t.co/hu92Y1FvaY

Congrats Iwijn! So wonderful to see ex-#CDlab members spread around the world and build their careers at many places. https://t.co/tGLiWD6HTO

Thanks to wonderful teams @cees_dekker #CDlab Wayne Yang @radhaboya @AndreGeim @DrYiYou1 @UoMPhysics and @aksimentievLab at UIUC, and @UoMGraphene @UoMChemistry Even DNA likes to swimthrough these ultra-smooth tunnels without much friction – please see https://t.co/AIwWEpRvw1 https://t.co/fvpkwW3vi2

Latest paper online: Translocation of DNA through ultrathin nanoslits https://t.co/4vicWmltBk Here, DNA slides through nm-thin graphene slits without friction! Great work by PhD student Wayne Yang of our #CDlab in collaboration with labs of @AKeerthi03 AndreGeim @aksimentievLab https://t.co/8IvVBWCi70

Our latest #CDlab paper is online: https://t.co/jsxkUdfOPF Here, @SiddhuLab and I wrote a brief review highlighting that in vitro (microfluidic) confinements like droplets and liposomes provide ideal opportunities for studying LLPS coacervation https://t.co/wgURv5rJvS

Our latest #CDlab paper online: https://t.co/342WOKyiFM PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA, in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores https://t.co/m6LKypiDkT

Congrats to @tudelft colleague Farbod Alijani for getting an @ERC proof-of-concept grant to develop graphene sensors for sensing single bacteria (to which our #CDlab may also will contribute a bit) https://t.co/5uvOaD5l9y https://t.co/lf624sf9Zx

Genome-in-a-box or GenBox? The name comes from the ‘particle-in-a-box’ models that provided basic insights in quantum mechanics. Similarly, using a bottom up biology approach we hope that GenBox may help to unravel key properties of chromosome organization. #CDlab #MoreToFollow https://t.co/cr6ZH0AHB2

Thanks to @martinholub_ @eugene_kim__ Jaco van der Torre and Aleksandre Japaridze for their discussions and feedback on the manuscript. As always, one never does science alone! #CDlab https://t.co/cYlxiEM7Q8

Paper online in @acsnano! In this perspective/review, @cees_dekker and I argue for a new in vitro approach to build and study chromosomes. Take megabasepair DNA, add individual chromosome building blocks, and build a chromosome from the bottom up. https://t.co/6ICzIW26dO #CDlab https://t.co/jgMYkpWMx4

Our latest #CDlab paper online in @acsnano! In this perspective/review, @AnthonyBirnie and I argue for a new in vitro approach to build and study chromosomes: Take megabasepair DNA, study individual building blocks, and then build a chromosome bottom up. https://t.co/5DrbXqfj7f https://t.co/K2c04stYcD

Here’s a very nice ‘Goodbye’ video by Korean postdoc @JeKyungRyu1 where he captured lots of informal nonscience aspects of our wonderfully social science group, the #CDlab: https://t.co/O0GSx1BhnO

On January 13, we organize an afternoon symposium on ‘New Technology in the Diagnostics of Poverty-related Parasitic Diseases’ All welcome to join in! Free admission, but register here: https://t.co/GnT9TDghlV #TUDelftGlobalInitiative #CDlab https://t.co/9ixQYDt18u

Latest #CDlab preprint on @biorxivpreprint: https://t.co/BlLyfZc7u0 We resolved individual steps of a condensin SMC while it extrudes loops of DNA – translocating DNA up to 600 bp/step with a step size of 20-45 nm. We find that ATP _binding_ generates the steps in loop extrusion https://t.co/WVuPGa6ho0

Dear #nanopore friends, don’t miss @cees_dekker ‘s talk this afternoon (2:40pm CEST). For the first time, he will present our #NEOtrap for long-term protein sensing using solid-state nanopores, plus many other exciting projects at #CDlab. See you online!😀 https://t.co/VIQXIQMp79