Latest #CDlab news
View #CDLab on Twitter Our latest #CDlab paper online: https://t.co/342WOKyiFM PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA, in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores https://t.co/m6LKypiDkT



Congrats to @tudelft colleague Farbod Alijani for getting an @ERC proof-of-concept grant to develop graphene sensors for sensing single bacteria (to which our #CDlab may also will contribute a bit) https://t.co/5uvOaD5l9y https://t.co/lf624sf9Zx
Genome-in-a-box or GenBox? The name comes from the ‘particle-in-a-box’ models that provided basic insights in quantum mechanics. Similarly, using a bottom up biology approach we hope that GenBox may help to unravel key properties of chromosome organization.
#CDlab #MoreToFollow https://t.co/cr6ZH0AHB2



Thanks to @martinholub_ @eugene_kim__ Jaco van der Torre and Aleksandre Japaridze for their discussions and feedback on the manuscript. As always, one never does science alone! #CDlab https://t.co/cYlxiEM7Q8
Paper online in @acsnano!
In this perspective/review, @cees_dekker and I argue for a new in vitro approach to build and study chromosomes.
Take megabasepair DNA, add individual chromosome building blocks, and build a chromosome from the bottom up. https://t.co/6ICzIW26dO #CDlab https://t.co/jgMYkpWMx4



Our latest #CDlab paper online in @acsnano!
In this perspective/review, @AnthonyBirnie and I argue for a new in vitro approach to build and study chromosomes:
Take megabasepair DNA, study individual building blocks, and then build a chromosome bottom up. https://t.co/5DrbXqfj7f https://t.co/K2c04stYcD



Here’s a very nice ‘Goodbye’ video by Korean postdoc @JeKyungRyu1 where he captured lots of informal nonscience aspects of our wonderfully social science group, the #CDlab: https://t.co/O0GSx1BhnO
On January 13, we organize an afternoon symposium on ‘New Technology in the Diagnostics of Poverty-related Parasitic Diseases’ All welcome to join in!
Free admission, but register here: https://t.co/GnT9TDghlV #TUDelftGlobalInitiative #CDlab https://t.co/9ixQYDt18u



Latest #CDlab preprint on @biorxivpreprint: https://t.co/BlLyfZc7u0 We resolved individual steps of a condensin SMC while it extrudes loops of DNA – translocating DNA up to 600 bp/step with a step size of 20-45 nm. We find that ATP _binding_ generates the steps in loop extrusion https://t.co/WVuPGa6ho0



Dear #nanopore friends, don’t miss @cees_dekker ‘s talk this afternoon (2:40pm CEST). For the first time, he will present our #NEOtrap for long-term protein sensing using solid-state nanopores, plus many other exciting projects at #CDlab. See you online!😀 https://t.co/VIQXIQMp79
Latest #CDlab paper online in @GHSPJournal: https://t.co/faaKkVEctx Matching development of point-of-care diagnostic tests to the local context: A case study of visceral leishmaniasis in Kenya and Uganda Great work by Michel Bengtson @mitashabharadw together with group @jcdiehl https://t.co/5lAD6G8Rsr



Our latest #CDlab paper is on @arxiv: https://t.co/VzP66nIGMe PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores https://t.co/tWQd6MSaHF



Our AFM paper is published in NSMB today in a collaboration with #CDlab and the Haering lab at EMBL. We suggested a scrunching model for SMC-protein-mediated DNA loop extrusion based on our observations. A HS-AFM movie of a condensin with ATP : https://t.co/u8Lu3BnQEE
Out now in @NatureSMB, our paper reporting liquid-AFM images of open and collapsed states of yeast condensin and the dynamic toggling between such states: https://t.co/0t2HaDYf5o Great job by postdoc @JeKyungRyu1 from our #CDlab in a collaboration with the Haering lab at EMBL. https://t.co/bKojIw7D4u



Refugees in the Netherlands with a MSc or PhD and relevant expertise in bio/nano/physics are welcome to contact me for a possible position in our #CDlab https://t.co/UxV0WyNBwc https://t.co/X8SP55XW2e
Heerlijke middag en avond gehad met alle leden van ons #CDlab: museum Voorlinden, kleiduiven schieten, beach volleybal en lekker een biertje en BBQ met alle partners en gezinnen bij een strandtent. Genieten! https://t.co/72FA0xWCm5



Openings for 4 PhD students and 4 Postdoctoral researchers for research on intrinsically disordered proteins in the Netherlands: https://t.co/pPGZh80hJ8 Join the great biologists / computational group at Groningen,
or our biophysics #CDlab at Delft: https://t.co/KYPrWGziVE https://t.co/nUXyIaMcNN



Postdoc and co-1st author @KevinDWhitley sketches the background story of our latest paper on the role of FtsZ treadmlling (https://t.co/AOnNDGudYl ) by @seamus_holden lab and our #CDlab: https://t.co/AlVQmwv6bx Artwork by @LizahvdA https://t.co/3e83eQ5F7j



So why is FtsZ actually treadmilling in bacterial cell division? @KevinDWhitley, a joint postdoc with @seamus_holden & our #CDlab, sorted it out: This is essential for Z-ring condensation and septal constriction initiation. Great work, now at @BioRxiv: https://t.co/AOnNDGudYl https://t.co/tW1SD4tTCH
Nice:
@AnneMirabella, senior editor of @NatureComms, selected our paper on imaging the circular chromosome of a bacterium (https://t.co/8fE0vXvn8o ) as a highlight of the past year: https://t.co/mrhw2kDjka Work led by postdocs @fabaiwu and Sandro Japaridze at our #CDlab https://t.co/YsovBMem2x



Our research lines
Our research ranges from the biophysics of DNA to synthetic cells and beyond.
More on our research linesOur team
View list of team membersOur biophysics lab hosts a very international group of researchers.
