Exploring life at the nanoscale
We significantly updated our #CDlab preprint paper about the step size of SMC proteins in DNA loop extrusion – see here for the new version on @biorxivpreprint: https://t.co/oLTkq9sb5y https://t.co/Y2EZDJzr29 
What is that #CDlab about? Our Bionanoscience department made a brief item introducing our group – including interviews with PhD students Sabrina Meindlhumer, @RomanBarth2, and @AlessioFragasso : https://t.co/AdZTA8GGhv
Cool paper out in @NatureComms by #BerndRieger/@SjoerdStallinga labs, to which our #CDlab also contributed: https://t.co/F3whWcUri4 Phase plate 2D imaging allows to determine both 3D position ànd orientation of a single fluorophore. Used this to optically image DNA supercoils! https://t.co/hzwaF15f7Y 
Latest paper #CDlab online:
‘FIB-milled plasmonic nanoapertures allow for long trapping times of individual proteins’ https://t.co/U8s8MopCdp Here, 1st author @Wayne_YangWW reports a FIB technique to make arrays of plasmonic nanopores that can hold single proteins for long times https://t.co/YHjx64TsdX 
New preprint of our #CDlab: “The archaeal division protein CdvB1 assembles into polymers that are depolymerized by CdvC” https://t.co/vP7lZnSZVX Here, we investigated some of the unique cell division machinery of archaea in vitro. Congrats to 1st author @abejota94 and coworkers https://t.co/2swmAw1Lis 
Latest #CDlab paper online: https://t.co/LNlhnljw9m In this perspective entitled “The NEOtrap – en route with a new single-molecule technique”, @sciSonja and me sketch many future directions and applications of the NEOtrap technique to trap and study a single protein. https://t.co/3KrKrTb7SF 
Probing nanomotion of single bacteria with graphene drums! Latest preprint from #CDlab in a great collaboration led by Farbod Alijani: https://t.co/mR9CPIDVzW Congrats to first authors Irek Roslon and @AleksandreJapa for a great job done https://t.co/fqFebO3V3f 
I wrote a personal ‘behind-the-paper blogpost’ about our #NEOtrap paper👇, with the aim to fight the ‘iceberg effect’ in academic publishing: https://t.co/jRqAc49HTe Maybe unusual. Curious to hear your comments. As a bonus: my original eureka-moment screenshots from #CDlab 🙂. https://t.co/W3m6IpDjGw
Thankful to @hendrik_dietz & Pierre for iterating with us through several designs, and for great discussions with @cees_dekker & the entire #CDlab #Nanoporito crew!
Our latest paper in @NatureNano: https://t.co/Diq1xqeJzs We developed a new type of single-molecule trap that can hold and study a single unlabeled protein for very long times. Superb work by @sciSonja (then a postdoc in our #CDlab, now PI at WUR), with @hendrik_dietz lab 1/ https://t.co/wwCgKtqaNL 
And here’s another #CDlab graduate who is starting her own lab as a PI! Make sure you’ll check out @DrJorine if you’re interested in live-cell chromosome biology! https://t.co/adYv21eJuI
Now on stage at @ebsa_in: @eugene_kim__, now a PI of her own group at MPI Frankfurt but today presenting her exciting postdoc work on SMC-driven DNA loops at our #CDlab https://t.co/jkYloh4UTU 
New perspective article out in @NatureComms:
Towards A Synthetic Cell Cycle! https://t.co/vbSvbNqHS6 By Lorenzo Olivi et al from John vanderOost lab & other @BaSyCresearch labs, with our #CDlab (Nicola De Franceschi & me) Read all about the challenges to build a synthetic cell. https://t.co/2nIW7tOPdc 
Can SMC proteins incorporate other DNA-bound proteins in extruded DNA loops? How do they deal with roadblocks? Read the story by postdoc Biswajit Pradhan from our #CDlab and our collaborators from the Jan-Michael Peters lab at IMP Vienna: https://t.co/zveKDE0DgX https://t.co/ybGA46PcUC 
Today we put out a preprint https://t.co/uJvpZLxXS1 where we resolve this question on how SMCs deal with obstacles bound to DNA –yielding quite some surprises! Great experiments by postdoc Biswajit Pradhan et al of our #CDlab, in collaboration with Jan-Michael Peters et al. 1/7 https://t.co/YScqfjlLbR 
Dit najaar komen er 4 nieuwe postdocs bij ons #CDlab, met heel internationale achtergrond (US, China, Estland, Italië). Er is nog ruimte voor meer nieuwe mensen, ook bv voor Nederlandse promovendi kandidaten – https://t.co/UxV0WyNBwc
New paper out today in @ACSSynBio: https://t.co/LAialMT1Bf Here, we report an optimized method for reconstituting biological systems in liposomes. Great team effort led by @KGanzinger and @gijsjekoenderi1, with contributions from @DanelonLab and our #CDlab. https://t.co/VCdxGMwqoL 
Latest preprint to which our #CDlab contributed: https://t.co/J2GpR5D4X6 https://t.co/f8jMfu26RP
Latest #CDlab paper in @acsnano: https://t.co/HkfryIyByQ Lead authors @AlessioFragasso & NicolaDeFranceschi show that we can make ultrawide (30nm) origami pores in liposomes that allow transmembrane transport of huge (250kDa) proteins. Great collaboration with @hendrik_dietz lab https://t.co/kysTRaBCpw 
