Our research ranges from the biophysics of DNA to synthetic cells and beyond. Please have a look below at the spectrum of our current projects.
The NEOtrap where a single protein is held in a nanopore that is capped with a DNA origami sphere
Using single-molecule optical and AFM imaging and force-spectroscopy techniques, we seek to unravel the mechanistic aspects of the structure and dynamics of chromosomes. Our research interests include:
Nanopores represent an elegant and versatile tool to measure single molecules. We research novel detection modes with solid-state nanopores as well as various ways to measure proteins with nanopores. Projects encompass the following:
Diagnostics for neglected diseases
We develop point-of-care diagnostics test of neglected tropical diseases within resource-limited settings, based on Crspr/Cas9 detecting of pathogen’s DNA in body fluids.